Head-Turning Transformations Of Millennial Celebs Who Used Ozempic Or Other GLP-1s

GLP-1 receptor agonists — the class of drugs that includes Ozempic, Wegovy, and Mounjaro — have reshaped conversations about weight management across Hollywood and beyond. For millennial celebrities in particular, a generation that grew up watching extreme diet culture and has since grappled publicly with body image issues, these medications have become a complex but increasingly open topic. Here's a look at the millennial stars who have spoken candidly about their experiences with these drugs.

Meghan Trainor — Open About Mounjaro

Meghan Trainor, the singer whose debut hit "All About That Bass" was itself a commentary on body positivity, has been refreshingly candid about using Mounjaro — the brand name for tirzepatide — to manage her weight after having children. Trainor has spoken about the medication in matter-of-fact terms, framing it as one tool among many in her overall approach to health. Her willingness to discuss it openly has helped destigmatize the conversation for many of her fans.

Whitney Leavitt — Semaglutide on Camera

Social media creator and influencer Whitney Leavitt documented her semaglutide journey directly to her audience, taking them along for the highs and lows in real time. Her transparency about the experience — including the side effects, the adjustments, and the results — resonated widely with followers who appreciated seeing the full, unfiltered picture rather than a carefully curated transformation reveal.

Remi Bader — An Honest Assessment

Model and body-positive content creator Remi Bader has spoken about trying both Ozempic and another GLP-1 medication, and her experience wasn't uniformly positive. She described becoming physically ill during her time on the drugs, and has been candid about the complicated emotional territory of using weight-loss medications as someone who has built a platform around body acceptance. Her story is a valuable counterpoint — a reminder that these medications don't work the same way for everyone.

Lauren Manzo — A Success Story

Lauren Manzo, daughter of Real Housewives star Caroline Manzo, has credited Mounjaro with helping her achieve weight-loss goals she'd struggled with for years. She's spoken positively about the experience and has been open with her social media followers about the role the medication played in her transformation. For Lauren, it appears to have been a genuinely effective intervention.

Bunnie Xo — Serious Side Effects

Podcaster and internet personality Bunnie Xo (wife of country singer Jelly Roll) had a far more alarming experience. She's spoken publicly about the serious side effects she encountered while using GLP-1 medications, describing a reaction severe enough to make her stop treatment. Her account is a stark reminder that while these drugs have helped many people, they come with real risks — and that celebrity enthusiasm for them shouldn't overshadow the importance of careful medical supervision.

Golnesa "GG" Gharachedaghi — Instagram Transparency

Shahs of Sunset star GG has been among the more visually transparent celebrities when it comes to her Ozempic journey, sharing her progress and her candid thoughts about the medication directly on Instagram. She hasn't shied away from the criticism that sometimes comes with such admissions, and her followers have largely responded with curiosity and support.

Claudia Oshry — Clear-Eyed About the Limits

Comedian and podcast host Claudia Oshry has talked openly about using GLP-1 medication while also being notably realistic about its limitations. She acknowledges that these drugs aren't a permanent fix — that weight management requires ongoing effort even with pharmaceutical assistance — and has been honest with her audience about the fact that medication alone isn't a long-term solution without supporting lifestyle changes.

Rebel Wilson — Maintenance Mode

Rebel Wilson, whose dramatic weight loss some years ago preceded the GLP-1 boom, has since spoken about using Ozempic on an intermittent basis to help maintain her results. Rather than relying on it continuously, she's described a more measured approach — using it as needed to support the habits she's already built. It's a nuanced take that reflects a more sophisticated understanding of what these medications can and can't do.

Chrissy Teigen — After the Hardest Year

Model and cookbook author Chrissy Teigen has spoken about turning to GLP-1 medication in the period following a devastating pregnancy loss. She has been transparent that her use of the drug came during an emotionally difficult chapter, noting it as part of her overall effort to take care of herself during an enormously painful time. Her willingness to contextualize the medication within her broader personal story adds a human dimension often missing from celebrity weight-loss conversations.

What connects all of these stories — the successes, the setbacks, the side effects — is the simple fact that these are real people dealing with real bodies and real pressures. GLP-1 medications have undeniably changed the landscape of weight management, but as these accounts make clear, they are not a one-size-fits-all solution, and the smartest voices on the topic are those who speak about them with nuance and honesty.